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The Daroff-Dell'Osso Ocular Motility Laboratory
(OMLAB)

Louis Stokes Cleveland Department of Veterans Affairs Medical Center
CASE School of Medicine
Case Western Reserve University
Cleveland, Ohio, USA

Measurement of Eye Movements to Study Neurological, Visual, and Vestibular Disorders; Ocular Motor System Function and Dysfunction

Areas of Specialization: Systems and Computational Neurobiology, Ocular Motor Oscillations (Nystagmus and Saccadic), Ocular Motor System Models, Nystagmus Therapies, Vision and Balance, Vestibular Function, Version-Vergence Interaction, Eye-Head Interactions, and Retinal Electrophysiology of Visual Disorders

Measurement techniques: Infrared Reflection, Magnetic Search Coil, and High-Speed Digital Video Systems to record eye movements in the horizontal, vertical and torsional planes of humans, canines, and mice; Motion platform and rotating chairs to study balance.

Links to Recent OMLAB Publications.

EBME319 students click here for laboratory information.

New! Maguire AM, et al: Safety and Efficacy of Gene Transfer for Leber's Congenital Amaurosis. (PubMed).

"From BENCH to BEDSIDE"inos2008 inos 2008
New! Abel LA, et al: Wavelet Analysis in Infantile Nystagmus Syndrome: Limitations and Abilities. (PubMed).
INOS Members Need to Knowinos2008 inos 2008
New! Wang ZI and Dell'Osso LF: Tenotomy Procedure Alleviates the "Slow to See" Phenomenon in Infantile Nystagmus Syndrome: Model Prediction and Patient Data. (PubMed).
New! Taibbi G, et al: Infantile Nystagmus Syndrome: Broadening the High-Foveation-Quality Field with Contact Lenses. Clin. Ophthalmol. 2008. (Free Download)..
New! Serra A, et al: Pseudo-Bruns' infantile nystagmus syndrome: mechanisms of jerk waveforms. (PubMed).
New! Bennicelli J, et al: Reversal of Blindness in Animal Models of Leber Congenital Amaurosis Using Optimized AAV2-mediated Gene Transfer. (PubMed).
New! Serra A, et al: Suppression of Saccadic Intrusions in Hereditary Ataxia by Memantine. (PubMed).
New! Liao K, et al: Vestibulo-ocular responses to vertical translation in normal human subjects. (PubMed).
New! Thurtell MJ, et al: Complete Ophthalmoplegia. An Unusual Sign of Bilateral Paramedian Midbrain-Thalamic Infarction. (PubMed).
New! Liao K, et al: Why do patients with PSP fall?: Evidence for Abnormal Otolith Responses. (PubMed).

New! Dell'Osso LF: The Benefits of Extraocular Muscle Surgery in Infantile Nystagmus Syndrome. (Reports & Teaching).
New! INS PATIENT HANDOUTS: 1. INS; 2. INS Treatments; 3. Tenotomy; 4. INS and Acuity; 5. INS Miscellaneous (Reports & Teaching).
New! CANINE EYE-MOVEMENT VIDEOS: Pre- and Post-Tenotomy (COMLAB).
[August 31, 2007] Updated: Dell'Osso LF: INOS 2008 - Ethical Science or Something Else? (The "Editorial Page").
INOS Members Need to Knowinos2008 inos 2008
New! Dell'Osso LF: Response to More than a Response: Tenotomy Improves INS Waveforms. (Reports & Teaching).inos2008 inos 2008

[May 3-4, 2007] OMLAB CONFERENCE (Conference 2007).

[September 2006] *** Dell'Osso LF: Original Ocular Motor Analysis of the First Human with Achiasma. *** (Reports & Teaching).
[May 2006] *** Come and browse our new lab space!.

[October 6, 2006] OMtools contains several updates and bug fixes, most notably in the "Graphing" toolbox.
[It should now work under Linux (and other case-sensitive file systems)] (Software).
[July 21, 2005] NAFX contains minor bug fixes and usability enhancements. (Software).

[November 22, 2005] Dell'Osso LF: Nystagmus Therapies: Types, Sites, and Measures. (Reports & Teaching).
[November 21, 2005] Dell'Osso LF: Using the NAFX for Eye-Movement Fixation Data Analysis and Display. (Reports & Teaching).
[January 11, 2005] Dell'Osso LF: Recording and Calibrating the Eye Movements of Nystagmus Subjects. (Reports & Teaching).

[July 30, 2004] Jacobs JB and Dell'Osso LF: Ocular Motor System model published in the Journal of Vision.
   Click here to read the paper (HTML). <==> Click here to download the paper (PDF).
   Click here to download OMS Model v1.0 (.zip).

Home   |   About OMLAB   |   Personnel   |   Software and OMS Models   |   Reports & Teaching   |   The "Editorial Page"   |   Contact Us 

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